Aliases for CHKA Gene
Aliases for CHKA Gene
External Ids for CHKA Gene
- HGNC: 1937
- Entrez Gene: 1119
- Ensembl: ENSG00000110721
- OMIM: 118491
- UniProtKB: P35790
Previous HGNC Symbols for CHKA Gene
- CHK
Previous GeneCards Identifiers for CHKA Gene
- GC11M067596
- GC11M067576
- GC11M067820
- GC11M064155
Summaries for CHKA Gene
-
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CHKA Gene
CHKA (Choline Kinase Alpha) is a Protein Coding gene. Diseases associated with CHKA include myositis and chanarin-dorfman syndrome. Among its related pathways are Phospholipase D signaling pathway and Glycerophospholipid biosynthesis. GO annotations related to this gene include protein homodimerization activity and signal transducer activity. An important paralog of this gene is CHKB.
UniProtKB/Swiss-Prot for CHKA Gene
-
Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CHKA Gene
Genomics for CHKA Gene
Regulatory Elements for CHKA Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GH110068059 | 4.2 | +61.7 | 1 | 0.4 |
-
|
5 genes
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Genomic Location:
chr11:68059567-68059935
Enhancer entries in source DBs:
FANTOM:
Enhancer-gene association evidence:
Other gene targets for enhancer:
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GH110068296 | 2.8 | -176.8 | 10 | 3.4 |
3 genes
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genomic Location:
chr11:68296571-68299966
Enhancer entries in source DBs:
FANTOM:
Ensembl:
ENCODE:
Enhancer-gene association evidence:
Transcription Factor Binding Sites within enhancer:
Other gene targets for enhancer:
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GH110068139 | 2.4 | -22.7 | 4 | 9.9 |
8 genes
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Genomic Location:
chr11:68139202-68149115
Enhancer entries in source DBs:
FANTOM:
Ensembl:
ENCODE:
Enhancer-gene association evidence:
Transcription Factor Binding Sites within enhancer:
Other gene targets for enhancer:
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GH110068471 | 2.3 | -350.7 | 16 | 1.9 |
6 genes
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Genomic Location:
chr11:68471162-68473077
Enhancer entries in source DBs:
FANTOM:
ENCODE:
Enhancer-gene association evidence:
Other gene targets for enhancer:
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| GH110068125 | 1.9 | -6.5 | 2 | 4.0 |
6 genes
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genomic Location:
chr11:68125959-68129987
Enhancer entries in source DBs:
FANTOM:
ENCODE:
Enhancer-gene association evidence:
Transcription Factor Binding Sites within enhancer:
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|---|---|---|
| ENSR00001804945 | 890 | 5201 |
- Transcription factor binding sites by QIAGEN in the CHKA gene promoter:
Regulatory Element Products
Genomic Location for CHKA Gene
- Chromosome:
- 11
- Start:
- 68,052,859 bp from pter
- End:
- 68,121,444 bp from pter
- Size:
- 68,586 bases
- Orientation:
- Minus strand
Genomic View for CHKA Gene
- Cytogenetic band:
-
- 11q13.2 by Ensembl
- 11q13.2 by Entrez Gene
- 11q13.1 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CHKA Gene
Proteins for CHKA Gene
-
Protein details for CHKA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P35790-CHKA_HUMAN
- Recommended name:
- Choline kinase alpha
- Protein Accession:
- P35790
- Q8NE29
Protein attributes for CHKA Gene
- Size:
- 457 amino acids
- Molecular mass:
- 52249 Da
- Quaternary structure:
-
- Heterodimer with CHKB (By similarity). Homodimer.
Three dimensional structures from OCA and Proteopedia for CHKA Gene
Protein Expression for CHKA Gene
Post-translational modifications for CHKA Gene
Other Protein References for CHKA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for CHKA (CHKA)
-
Custom Antibody ServicesOriGene Antibodies for CHKA
- Novus Biologicals Antibodies for CHKA
- Abcam antibodies for CHKA (P35790)
- Invitrogen Antibodies for CHKA
- antibodies-online Antibodies for CHKA: See all 50
- Search GeneTex for Antibodies for CHKA
-
Santa Cruz Biotechnology (SCBT) Antibodies for CHKA See all 5 » See less «
Protein Products
-
- Search Origene for MassSpec and Protein Over-expression Lysates for CHKA
- Origene Custom Protein Services for CHKA
- antibodies-online Proteins for CHKA: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CHKA
Assay Products
- antibodies-online Kits for CHKA: See all 5
No data available for DME Specific Peptides for CHKA Gene
Domains & Families for CHKA Gene
Protein Domains for CHKA Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CHKA Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P35790- Family:
-
- Belongs to the choline/ethanolamine kinase family.
No data available for Gene Families for CHKA Gene
Function for CHKA Gene
Molecular function for CHKA Gene
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=0.2 mM for choline {ECO:0000269 PubMed:17007874, ECO:0000269 PubMed:19915674}; KM=0.4 mM for ATP {ECO:0000269 PubMed:17007874, ECO:0000269 PubMed:19915674}; KM=12 mM for ethanolamine {ECO:0000269 PubMed:17007874, ECO:0000269 PubMed:19915674};
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + choline = ADP + phosphocholine.
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + ethanolamine = ADP + O-phosphoethanolamine.
- UniProtKB/Swiss-Prot Function:
- Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Enzyme Numbers (IUBMB) for CHKA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004103 | choline kinase activity | TAS | |
| GO:0004104 | cholinesterase activity | IEA | |
| GO:0033265 | choline binding | IEA |
Phenotypes for CHKA Gene
- MGI mutant phenotypes for CHKA:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CHKA:
-
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
- Increased transferrin (TF) endocytosis
- Decreased viability
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after viral supernatant infection
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection after direct virus infection
- Decreased human cytomegalovirus (HCMV) strain AD169 replication
- Decreased cell proliferation
- Condensed cis-Golgi
- Decreased cella89culturea89derived Hepatitis C virus (HCVcc
- Decreased Hepatitis C Virus pseudoparticles (HCVpp
Animal Model Products
-
Taconic Biosciences Mouse Models for CHKA
-
ViGene Biosciences lentiviral particle packaged cDNA for CHKA gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CHKA gene
- Search ViGene Biosciences for CHKA
CRISPR Products
-
OriGene CRISPR knockouts for CHKA
-
Santa Cruz Biotechnology (SCBT) CRISPR for CHKA See all 3 » See less «
- GenScript: Design CRISPR guide RNA sequences for CHKA
miRNA for CHKA Gene
- miRTarBase miRNAs that target CHKA
miRNA Products
- Search ViGene Biosciences for CHKA
Clone Products
- OriGene clones in human for CHKA
- OriGene ORF clones in human,mouse,rat for CHKA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CHKA
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CHKA gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CHKA gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CHKA gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CHKA Gene
Localization for CHKA Gene
Subcellular locations from UniProtKB/Swiss-Prot for CHKA Gene
- Cytoplasm.
No data available for Gene Ontology (GO) - Cellular Components for CHKA Gene
Pathways & Interactions for CHKA Gene
| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Glycerophospholipid biosynthesis | ||
| 2 | Metabolism |
| |
| 3 | Phospholipase D signaling pathway | ||
| 4 | Ca, cAMP and Lipid Signaling | ||
| 5 | Acetylcholine Synthesis |
Pathways by source for CHKA Gene
1 Cell Signaling Technology pathway for CHKA Gene
2 BioSystems pathways for CHKA Gene
3 KEGG pathways for CHKA Gene
UniProtKB/Swiss-Prot P35790-CHKA_HUMAN
- Pathway: Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphocholine from choline: step 1/1.
- Pathway: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
Interacting Proteins for CHKA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006580 | ethanolamine metabolic process | IEA | |
| GO:0006629 | lipid metabolic process | TAS | 10363580 |
| GO:0006644 | phospholipid metabolic process | TAS | |
| GO:0006646 | phosphatidylethanolamine biosynthetic process | TAS | |
| GO:0006656 | phosphatidylcholine biosynthetic process | TAS |
No data available for SIGNOR curated interactions for CHKA Gene
Drugs & Compounds for CHKA Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Approved
| Nutra | Enzyme, substrate | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Adenosine triphosphate
26
|
Approved
| Nutra | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Experimental
| Pharma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Ethanolamine
26
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Experimental
| Pharma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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O-Phosphoethanolamine
26
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Experimental
| Pharma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|---|---|---|---|---|
| ADP 23 26 |
| Full agonist, Agonist | 58-64-0 | ||
| PC(18:1(9Z)e/2:0) 26 |
| ||||
| Phosphatidylcholines Group A 26 |
| 63-89-8, 68737-67-7 | |||
| Phosphatidylcholines Group B 26 |
| 88542-95-4 |
Transcripts for CHKA Gene
mRNA/cDNA for CHKA Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (156) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CHKA
-
Santa Cruz Biotechnology (SCBT) CRISPR for CHKA See all 3 » See less «
- GenScript: Design CRISPR guide RNA sequences for CHKA
miRNA Products
- Search ViGene Biosciences for CHKA
Clone Products
- OriGene clones in human for CHKA
- OriGene ORF clones in human,mouse,rat for CHKA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CHKA
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | · | 13d | ^ | 14a | · | 14b | · | 14c | · | 14d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||||
| SP6: |
Expression for CHKA Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for CHKA Gene
SOURCE GeneReport for Unigene cluster for CHKA Gene Hs.77221
Primer Products
-
OriGene qPCR primer pairs for CHKA
-
OriGene qPCR primer pairs and template standards for CHKA
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CHKA Gene
Orthologs for CHKA Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | CHKA 35 |
|
||
| CHKA 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | CHKA 35 |
|
||
| CHKA 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Chka 35 |
|
||
| Chka 16 |
|
||||
| Chka 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | CHKA 35 |
|
||
| CHKA 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Chka 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CHKA 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CHKA 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CHKA 35 |
|
||
| CHKA 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | CHKA 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | chka 35 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.12834 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | chka 35 |
|
||
| chka 36 |
|
OneToOne | |||
| fruit fly (Drosophila melanogaster) |
Insecta | CG2201 36 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | cka-2 35 |
|
||
| cka-1 36 |
|
ManyToMany | |||
| cka-2 36 |
|
ManyToMany | |||
| ckb-1 36 |
|
ManyToMany | |||
| ckb-2 36 |
|
ManyToMany | |||
| ckb-3 36 |
|
ManyToMany | |||
| ckb-4 36 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CKI1 36 |
|
ManyToMany | |
| EKI1 36 |
|
ManyToMany | |||
| EKI1 38 |
|
|
|||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | CK1 35 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0183000 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany |
- Species with no ortholog for CHKA:
-
- A. gosspyii yeast (Ashbya gossypii)
- See all 39 »
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- See less «
Paralogs for CHKA Gene
(2) SIMAP similar genes for CHKA Gene using alignment to 3 proteins:
Variants for CHKA Gene
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs17853641 5 4 | - | 68,070,830(+) | CAAAC(C/T)TAATT | nc-transcript-variant, reference, missense | |
| rs17853642 5 4 | - | 68,062,002(+) | ACCAC(A/T)GTCCC | nc-transcript-variant, reference, missense | |
| rs1703431 5 | -- | 68,055,847(-) | ggctg(A/G)tctcg | intron-variant | |
| rs1703432 5 | -- | 68,055,842(-) | gtctc(A/G)aactc | intron-variant | |
| rs1703439 5 | -- | 68,080,361(+) | ttttt(C/T)gcatt | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv394e1 | CNV | Complex | 17122850 |
| nsv469856 | CNV | Gain | 16826518 |
| dgv1203n71 | CNV | Loss | 21882294 |
| dgv1204n71 | CNV | Loss | 21882294 |
| nsv825963 | CNV | Gain | 20364138 |
| nsv469964 | CNV | Loss | 18288195 |
| dgv1207n71 | CNV | Loss | 21882294 |
| nsv897852 | CNV | Gain | 21882294 |
| dgv1208n71 | CNV | Loss | 21882294 |
| nsv897855 | CNV | Loss | 21882294 |
| nsv825965 | CNV | Gain | 20364138 |
| esv2677355 | CNV | Deletion | 23128226 |
| nsv371 | CNV | Loss | 18451855 |
Relevant External Links for CHKA Gene
- HapMap Linkage Disequilibrium report
- CHKA
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CHKA Gene
Disorders for CHKA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myositis 1 23 |
| |
| chanarin-dorfman syndrome 1 |
| |
| muscle disorders 1 |
| |
| leukomalacia 1 | ||
| microinvasive gastric cancer 23 |
|
Relevant External Links for CHKA
No data available for UniProtKB/Swiss-Prot and Genatlas for CHKA Gene
Publications for CHKA Gene
- Cloning of a human choline kinase cDNA by complementation of the yeast cki mutation. (PMID: 1618328) Hosaka K. … Yamashita S.(FEBS Lett. 1992)
- 2
- 3
- 4
- 67
- Structure and function of choline kinase isoforms in mammalian cells. (PMID: 15003397) Aoyama C. … Ishidate K.(Prog. Lipid Res. 2004)
- 2
- 3
- 23
- Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment. (PMID: 19915674) Gallego-Ortega D. … Lacal J.C.(PLoS ONE 2009)
- 3
- 23
- Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model. (PMID: 18172309) Glunde K. … Bhujwalla Z.M.(Cancer Res. 2008)
- 3
- 23
- Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy. (PMID: 18296102) RamA-rez de Molina A. … Lacal J.C.(Int. J. Biochem. Cell Biol. 2008)
- 3
- 23
Products for CHKA Gene
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- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CHKA
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for CHKA
- Origene Custom Protein Services for CHKA
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for CHKA
- Browse OriGene Inhibitory RNA Products For CHKA
- OriGene qPCR primer pairs for CHKA
- OriGene qPCR primer pairs and template standards for CHKA
- OriGene CRISPR knockouts for CHKA
- OriGene clones in human for CHKA
- OriGene ORF clones in human,mouse,rat for CHKA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for CHKA
- GenScript Custom Assay Services for CHKA
- GenScript Custom overexpressing Cell Line Services for CHKA
- GenScript: Design CRISPR guide RNA sequences for CHKA
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CHKA
- Cell Signaling Technology (CST) Antibodies for CHKA (CHKA)
- Search for Antibodies & Assays
- Novus Biologicals Antibodies for CHKA
- Novus Biologicals proteins and lysates for CHKA
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for CHKA
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Addgene plasmids for CHKA
- antibodies-online Antibodies for CHKA: See all 50
- antibodies-online Kits for CHKA: See all 5
- antibodies-online Proteins for CHKA: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for CHKA
- Search GeneTex for Proteins for CHKA
- ViGene Biosciences adenoviral particle packaged cDNA for CHKA gene
- ViGene Biosciences lentiviral particle packaged cDNA for CHKA gene
- ViGene Biosciences lentiviral particle packaged cDNA for CHKA gene
- ViGene Biosciences ready-to-package AAV shRNAs for CHKA gene
- ViGene Biosciences ready-to-package AAV shRNAs for CHKA gene
- ViGene Biosciences ready-to-package AAV shRNAs for CHKA gene
- Search ViGene Biosciences for CHKA
- Search ViGene Biosciences for CHKA
- Santa Cruz Biotechnology (SCBT) Antibodies for CHKA See all 5 » See less «
- Search Santa Cruz Biotechnology (SCBT) for CHKA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CHKA See all 3 » See less «
Sources for CHKA Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon






More details on SuperPathways for CHKA
